23 July 2019

Whole-body MRI scans are as accurate as standard imaging pathways for lung cancer staging - the Streamline L trial.

Whole-body MRI scans are as accurate as standard imaging pathways for lung cancer staging - the prospective Streamline L trial.
NIHR Signal 23 July 2019
  • Using whole-body magnetic resonance imaging (WB-MRI) in the initial investigation pathway is as good as standard pathways for detecting metastatic disease in adults with non-small-cell lung cancer. The study (Streamline L trial) also found that WB-MRI used for diagnosis and staging is quicker, cheaper and requires fewer other investigations than standard pathways.
  • Current NICE guidance recommends a sequence of investigations for staging – assessing the extent of cancer in order to plan appropriate treatment. MRI of different areas of the body is only recommended after other imaging investigations. This study suggests that whole-body MRI could have a role earlier in the pathway.
  • Study: The Streamline L trial was a prospective, multicentre trial done in 16 hospitals in Englandca rried out between 26 Feb 2013 and 5 Sept 2016. 976 patients were screened for eligibility. 353 patients were recruited, 187 of whom completed the trial.