BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the ICU

BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization.
Cochrane Database of Systematic Reviews 2018, Issue 2. Art. No.: CD011240. DOI: 10.1002/14651858.CD011240.pub2.

• A systematic review identified four studies (n=256) of low- or very low-quality, providing insufficient evidence about the effects of BIS monitoring for sedation in critically ill mechanically ventilated adults on clinical outcomes or resource utilisation.